This study is being conducted in New Zealand. Regions covered: Christchurch (paediatrics and adults), Dunedin (paediatrics only), Auckland (paediatrics only) and Hamilton (adults only).
The study will examine the safety and efficacy of the reference design algorithm for both children and adults. The algorithm and app interface being tested is based on AndroidAPS, one of the two implementations of the OpenAPS algorithm. The study is funded by the Health Research Council of New Zealand.
We are not yet ready to recruit participants. Recruitment will be via DHBs diabetes services and potential participants will have to meet specific criteria. Recruitment will begin in early 2020.
The protocol for the study is currently being finalized, and initial recruitment for the study is planned for early 2020.
Publications go here.
Dr de Bock, a paediatric endocrinologist, is the primary investigator for the study. He has extensive experience running large, multi-site diabetes technology studies.
Ms Lewis is the co-investigator for the study and is the founder of the do-it-yourself artificial pancreas system movement. She has collaborated extensively to develop a range of research projects in relation to do-it-yourself diabetes technologies, and wrote the first book on closed loop automated insulin delivery.
Dr Crocket is a social scientist, whose research focuses on learning and self-management practices in relation to diabetes technologies. He is a person with diabetes and an AndroidAPS user.
Associate Professor Ben Wheeler, a paediatric endocrinologist, is responsible for the Dunedin study site.
Associate Professor Craig Jefferies, a paediatric endocrinologist is responsible for the Auckland study site.
Dr Ryan Paul, an endocrinologist, is responsible for the Hamilton study site.
Automated insulin delivery, another name for the technology used in an ‘artificial pancreas system’, integrates an insulin pump and a continuous glucose monitor with an algorithm to automatically adjust insulin delivery in real time.
A do-it-yourself artificial pancreas system. These have been created by people affected by type one diabetes and made available, via open-source software and online support groups.
The first DIY APS to have been developed. It has been written by people affected by diabetes with the aim of improving safety, glycaemic control and quality of life. See https://openaps.org
AndroidAPS is an Android-specific app that deploys the OpenAPS algorithm. See here
Sensor-augmented pump therapy is the use of a continuous glucose monitor alongside an insulin pump for managing type one diabetes. It is the current standard of care that outcomes from automated insulin delivery trials are most commonly compared to. The main difference is that in SAPT there is no algorithm driving adjustments of insulin delivery; the person with type 1 diabetes does all insulin dosing adjustments manually.
If you’re not eligible for the study but want to learn more about automated insulin delivery, this book is a good resource to introduce you to commercial and do-it-yourself artificial pancreas system options.
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